Projects

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  CRISPR dynamics in Bombella strains isolated from longitudinal sampling of honey bee larvae

  Core Project

  CRISPR-Cas immunity tracks host-microbe interactions. Researchers aim to study CRISPR dynamics in natural populations and their impact on symbiont evolution using Bombella from bee larvae.

Publications

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  Miller et al., 2026

  Miller, D.L., Caesar, L., Ganote, C., López-Madrigal, S., Rice, D.W., Robinson, C.R.P., Seawright, A.M., Lewis, J.P., & Newton, I.L.G. (2026). Nested connections: Local phage and broad plasmid sharing in the honey bee mobilome. bioRxiv. 

  https://doi.org/10.1101/2025.10.31.685865
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  Ganote et al., 2025

  Ganote, C., Caesar, L., Rice, D. W., Whitaker, R. J., & Newton, I. L. G. (2025). Evolutionary trends in Bombella apis CRISPR-Cas systems. mSystems 0:e00166-25.

  https://doi.org/10.1128/msystems.00166-25
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  Caesar et al., 2024

  Caesar, L., Rice, D. W., McAfee, A., Underwood, R., Ganote, C., Tarpy, D. R., Foster, L. J., & Newton, I. R. L. (2024). Metagenomic analysis of the honey bee queen microbiome reveals low bacterial diversity and Caudoviricetes phage. mSystems, 9:e01182-23.

  https://doi.org/10.1128/msystems.01182-23