- Many bacteria are infected by viruses, but their evolutionary effects are understudied.
- Researchers explore how viral fitness evolves with enforced vertical transmission.
- Hosts may adapt to viruses before adapting to the environment.
Description
A large majority of all sequenced bacterial isolates are latently infected by viruses; however, our understanding of how the viruses affect the evolutionary trajectories of their partners is understudied, and the benefit to the viruses within this context is often considered only from a bacterial perspective. Graduate student Laura Suttenfield and Rachel Whitaker, in collaboration with James Slauch and Zoi Rapti, propose to assess how viral fitness evolves in a context where vertical transmission is enforced by a lack of susceptible hosts. They hypothesize that selection for viral vertical transmission results in lowered spontaneous induction of the virus and adaptation of the hosts to their virus before the environment.
People on this Project
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Laura Suttenfield
Project LeadGraduate Student
University of Illinois Urbana-Champaign
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Rachel Whitaker
Project LeadCo-PI; Professor of Microbiology
University of Illinois Urbana-Champaign
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Zoi Rapti
Project ContributorProfessor of Mathematics
University of Illinois Urbana-Champaign
Publications
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Suttenfield et al., 2024
Suttenfield, L. C., Rapti, Z., Chandrashekhar, J. H., Steinlein, A. C., Vera, J. C., Kim, T., & Whitaker, R. J. (2024). Phage-mediated resolution of genetic conflict alters the evolutionary trajectory of Pseudomonas aeruginosa lysogens. mSystems, 9:e00801-24.
https://doi.org/10.1128/msystems.00801-24