Investigator, Howard Hughes Medical Institute and Professor, School of Life Sciences
Arizona State University
Dr. John McCutcheon and his group study bacteria (and sometimes fungi) that form long-term infections in host cells. Most of the symbioses his lab studies are beneficial, where the intracellular bacteria provide essential nutrients to their hosts, but he is also interested in transitions between pathogenic and beneficial infections. His group studies how and why symbioses form, how they are maintained, and why they sometimes breakdown. They use a variety of approaches—cell biology, genetics, genomics, microscopy, molecular biology, molecular evolution, biochemistry, and field biology—to address their questions.